Endometrial receptivity array

It's a diagnostic test used in the field of reproductive medicine to assess the receptivity of the uterine lining for embryo implantation.

Overview

The endometrial receptivity array (ERA) is a diagnostic test used in the field of reproductive medicine to assess the receptivity of the uterine lining (endometrium) for embryo implantation. It helps determine the optimal timing for embryo transfer in in vitro fertilization (IVF) or other assisted reproductive techniques.

The ERA test involves taking a small biopsy of the endometrial tissue lining the uterus. The biopsy is usually performed in a woman’s natural menstrual cycle or in a controlled hormone replacement cycle, depending on the specific protocol used by the fertility clinic. The biopsy sample is then analyzed to assess the gene expression profile of certain markers related to endometrial receptivity.

Here is an overview of the ERA process:

  1. Biopsy Procedure: The endometrial biopsy is typically performed in an outpatient setting. It involves the insertion of a thin catheter through the cervix into the uterus to obtain a small tissue sample from the endometrium. The procedure may cause mild discomfort or cramping, similar to menstrual cramps.

  2. Sample Analysis: The endometrial tissue sample is sent to a laboratory where the gene expression analysis is performed. The expression levels of specific genes associated with endometrial receptivity are evaluated. This analysis helps determine if the endometrium is in the receptive state for embryo implantation or if it requires adjustments in the timing of embryo transfer.

  3. Personalized Timing Assessment: Based on the gene expression analysis, the results of the ERA test will indicate whether the endometrium is receptive or non-receptive at the time of the biopsy. If the endometrium is found to be non-receptive, the test can help identify the optimal window of implantation, which may be shifted compared to the standard timing.

  4. Adjusted Embryo Transfer: With the information obtained from the ERA test, the timing of the embryo transfer can be personalized and adjusted accordingly. This can improve the chances of successful implantation and pregnancy.

The ERA test is typically recommended for women who have experienced repeated implantation failure in previous IVF cycles or for those with unexplained infertility. It allows fertility specialists to individualize the timing of embryo transfer based on the specific needs of each patient.

It’s important to note that the ERA test is still a relatively new diagnostic tool, and further research is being conducted to establish its effectiveness and determine the specific patient populations that may benefit the most from it. It is advisable to consult with a fertility specialist or reproductive endocrinologist to discuss whether the ERA test is appropriate for your specific situation and to understand its potential benefits and limitations.

InduMadhusudhan-MBBSMD-ObstetricsGynaecology

Dr. Indu Madhusudhan

MBBS, MD - Obstetrics & Gynaecology

Speciality : Infertility Specialist, Gynecologist, Obstetrician Experience : 22+ Years Experience
Languages spoken : English, Kannada ,Hindi , Marathi

MadhusudhanHR-MS-GeneralSurgeryMCh-UrologyGenito-UrinarySurgeryDNB-UrologyGenito-UrinarySurgeryMNAMS-GeneralSurgeryFRCS-GeneralSurgeryMBBS

Dr. Madhusudhan H.R

MS - General Surgery, MCh - Urology/Genito-Urinary Surgery, DNB - Urology/Genito - Urinary Surgery, MNAMS - General Surgery, FRCS - General Surgery, MBBS

Speciality : Infertility Specialist, Gynecologist, Obstetrician Experience : 22+ Years Experience
Languages spoken : English, Kannada ,Hindi , Marathi

Sushma Dasari
Sushma Dasari
2022-12-30
It’s a gods grace to meet Dr.Indu Madhusudhan, our life has changed completly because of her advices, I am conceived now and expecting a baby in few days. She is extremely patient friendly, polite and smiling in addressing all our concerns. More to it she also made us feel comfortable in communicating freely during the appointments. I would say she is one of the top most gynaecologist with impeccable knowledge. Thank you mam for utmost care and advices.
Suseela kurakula
Suseela kurakula
2022-12-24
Very good consultation…and preferable
vinutha prabhakar
vinutha prabhakar
2022-10-17
I have known Dr.Indu for over a year now. She is extremely kind and helpful. Patiently addressed all our concerns. She has such a positive aura which is calming. She has been of great support in my pregnancy journey! I am so glad to have consulted her. Thank you, Doctor.
Srujana Banjagere
Srujana Banjagere
2022-09-07
Extremely kind and empathetic. carefully investigates your entire history and explains the options available. Doctor is very transparent and knowledgeable. She also has a soothing aura. Definitely recommend to anyone trying for a baby.
sonali manure
sonali manure
2022-05-17
Doctor is very professional and friendly. I am so grateful to have met her. 🙂🙏
Pratibha Kulkarni
Pratibha Kulkarni
2021-11-13
We are thankful to Dr.Indu for always being there for us. Throughout our infertility journey she gave us hope and encouraged us to not give up. We really appreciate her knowledge, friendliness and frankness. Her calm demeanour and constant guidance helped us keep calm through our challenging pregnancy and emergency c-section. She has not just been our doctor but also a friend and a guide.

Frequently Asked Questions

Before your first appointment, one of our clinical care coordinators will call you to discuss your case and review what appointments to expect. The clinical care coordinator will make sure all appointments are arranged in a timely fashion. Each of our patients is unique and treated individually, and the schedule of doctors you see will be tailored specifically to your needs. The doctors will discuss your care options with you and answer any questions that you may have regarding your diagnosis and management.

We are dedicated to helping pregnant women and their families after a significant birth defect or genetic condition has been detected. Specialists from both obstetrics and pediatrics work together as a team to determine the best way to care for you and your unborn baby, both during and after your pregnancy.

Whenever possible, we create an integrated appointment plan, so that you can meet with the multiple subspecialists involved in your case. Some patients come here for a second opinion and go back to their obstetrician. Other patients transfer their care to Columbia as their delivery date approaches to make sure their baby immediately receives the necessary specialized pediatric care after birth.

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