The Impact of Medications on Fertility: What You Need to Know

Understanding How Medications Can Influence Fertility in Men and Women

When planning for a family, most people focus on lifestyle, diet, and timing—but medications are often overlooked. Many commonly used drugs, whether prescription, over-the-counter, or herbal, can have a significant impact on fertility in both men and women.

Whether you’re actively trying to conceive or just preparing for the future, understanding how medications influence reproductive health is crucial. At Samrudh Fertility and Urology Centre, located in Kumaraswamy Layout, Bangalore, Dr. Indu Madhusudan provides expert guidance on navigating fertility while managing medical treatments.

How Medications Affect Female Fertility

1. Hormonal Disruptions

Certain medications, especially those that affect the endocrine system, can interfere with ovulation. These include:

  • Antidepressants (especially SSRIs)
  • Antipsychotics
  • Corticosteroids These can disturb hormone levels that regulate the menstrual cycle, potentially causing irregular periods or even amenorrhea (absence of menstruation).

 

2. Chemotherapy and Radiation

Cancer treatments, particularly chemotherapy drugs like cyclophosphamide, can harm ovarian function, sometimes leading to premature ovarian failure. Women undergoing these treatments may consider fertility preservation options like egg freezing.

3. NSAIDs and Pain Relievers

Prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, can impact ovulation by suppressing the release of eggs from the ovaries.

How Medications Affect Male Fertility

1. Hormonal Medications

Anabolic steroids and testosterone replacement therapy may suppress the body’s natural production of sperm. Even after stopping usage, it can take months for sperm production to return to normal.

2. Certain Antibiotics

Some antibiotics, such as nitrofurantoin and erythromycin, have been linked to temporary sperm motility issues or reduced sperm count.

3. Chemotherapy

Just like in women, chemotherapy drugs can damage sperm production. Sperm banking is highly recommended before starting treatment.

4. Other Medications That May Reduce Sperm Quality
  • Anti-hypertensive drugs (e.g., calcium channel blockers)
  • Anti-seizure medications
  • Antidepressants (may lead to ejaculation issues)

Over-the-Counter and Herbal Medications

Many people assume herbal remedies are safe, but some herbal supplements can negatively affect reproductive health. For example:

  • St. John’s Wort (often used for depression) may lower sperm motility.
  • Ginseng can affect testosterone levels.
  • Dong quai and black cohosh, commonly used for hormonal balance, may interfere with ovulation when misused.

Always consult your fertility specialist before using any alternative medicine.

What You Should Do Before Trying to Conceive

Medical Review

Before trying to conceive, schedule a preconception consultation with your doctor or fertility specialist. Bring a list of:

  • All current medications (prescription, OTC, herbal)
  • Medical history and conditions
  • Recent lab reports if available

Your doctor may recommend switching or tapering certain medications or adjusting treatment plans to support reproductive goals.

Consider Medication Alternatives

If a medication is known to impair fertility, your doctor might offer alternatives that are safer for conception without compromising your overall health.

Expert Care at Samrudh Fertility and Urology Centre

Under the guidance of Dr. Indu Madhusudan, with over 22 years of experience in fertility care, patients at Samrudh Fertility receive comprehensive evaluations that consider all possible factors—including medications—that could impact conception.

With a personalized approach, Dr. Indu ensures that every couple understands how their medications interact with fertility, offering solutions that prioritize both health and pregnancy success.

Conclusion

Medications play a vital role in managing health conditions, but they can also affect fertility in subtle and significant ways. By consulting a fertility expert, reviewing current treatments, and making informed choices, couples can increase their chances of successful conception. At Samrudh Fertility and Urology Centre in Bangalore, Dr. Indu Madhusudan provides the expertise and compassionate care needed for a healthy, well-informed fertility journey.

Facebook
Twitter
Email
Print

Reception

Typically replies within a day

Hello, Welcome to the Samrudh Fertility and Urology Centre. Please click below button for talking me through phone call.

Book an appointment

We are leading doctors in gynecology and urology  fell free to take and appointment with us.