What Is Unexplained Infertility? How Is It Treated?

Understanding Unexplained Infertility: Causes, Diagnosis & Treatment

Infertility can be a distressing journey for couples trying to conceive. While some infertility cases have clear medical explanations, unexplained infertility occurs when standard fertility tests reveal no identifiable cause. This condition affects nearly 10-15% of couples facing conception difficulties.

If you are struggling with infertility without a clear diagnosis, Samrudh Fertility and Urology Centre in Bangalore, led by Dr. Indu Madhusudan, offers advanced treatment options to help couples achieve their dream of parenthood.

What Is Unexplained Infertility?

Unexplained infertility is diagnosed when:

  • Ovulation is normal (no hormonal imbalances or ovulatory disorders detected).
  • Semen analysis is healthy (sperm count, motility, and morphology are within normal range).
  • Fallopian tubes are open (confirmed through HSG or laparoscopy).
  • No other medical conditions (like endometriosis or uterine abnormalities) are detected.

Despite normal test results, couples still struggle to conceive naturally, leading to frustration and emotional distress.

Possible Causes of Unexplained Infertility

Although medical tests may not reveal a specific cause, several hidden factors can contribute to unexplained infertility:

1. Egg and Sperm Quality Issues
  • Poor egg quality, despite regular ovulation, can hinder fertilization.
  • DNA fragmentation in sperm can affect embryo development, even if sperm count is normal.
2. Implantation Failure
  • The embryo may fail to attach to the uterine lining due to inflammation, immune system issues, or thin endometrial lining.
3. Mild Endometriosis
  • Small endometrial growths can go undetected in initial fertility tests but still impact conception.
4. Cervical Mucus Hostility
  • Thick or acidic cervical mucus can make it difficult for sperm to reach the egg.
5. Lifestyle and Environmental Factors
  • Stress, diet, weight fluctuations, smoking, and environmental toxins can subtly impact fertility.

How Is Unexplained Infertility Diagnosed?

At Samrudh Fertility and Urology Centre, Dr. Indu Madhusudan performs advanced fertility evaluations, including:

  • Ovarian reserve testing (AMH levels, antral follicle count).
  • DNA fragmentation test for sperm quality.
  • Endometrial receptivity assessment to check uterine health.
  • Immunological testing to detect autoimmune issues affecting implantation.

Treatment Options for Unexplained Infertility

Although the cause is unclear, several treatment options can improve conception chances:

1. Lifestyle Modifications
  • Maintain a healthy diet rich in fertility-boosting nutrients.
  • Manage stress through yoga, meditation, or therapy.
  • Limit caffeine, alcohol, and smoking.
2. Ovulation Induction and Timed Intercourse
  • Medications like Clomiphene Citrate or Letrozole stimulate ovulation, increasing conception chances.
  • Timed intercourse ensures sperm meets the egg at the most fertile period.
3. Intrauterine Insemination (IUI)
  • Sperm is washed and directly inserted into the uterus to bypass potential cervical mucus issues.
  • Ideal for mild fertility concerns and unexplained infertility cases.
4. In Vitro Fertilization (IVF)
  • Eggs are retrieved and fertilized in a controlled lab setting before being implanted into the uterus.
  • Advanced techniques like ICSI (Intracytoplasmic Sperm Injection) can help overcome subtle sperm issues.
  • PGT (Preimplantation Genetic Testing) ensures healthy embryos before implantation.
5. Endometrial Receptivity Analysis (ERA)
  • Checks if the uterus is receptive to embryo implantation, optimizing IVF success rates.

Best Fertility Clinic for Unexplained Infertility in Bangalore

For couples in Kumaraswamy Layout, Bangalore, struggling with unexplained infertility, Samrudh Fertility and Urology Centre provides expert diagnosis and personalized treatment. Dr. Indu Madhusudan specializes in fertility solutions, offering hope to couples with unexplained conception challenges.

Conclusion

Unexplained infertility can be emotionally challenging, but effective treatments exist. With the right medical support, lifestyle changes, and advanced reproductive technologies, many couples successfully conceive.

If you’re facing unexplained infertility in Bangalore, consult Dr. Indu Madhusudan at Samrudh Fertility and Urology Centre to explore personalized fertility solutions.

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